Lancet 1984 Jun 23;1(8391):1382-3

Heart-liver transplantation in a patient with familial hypercholesterolaemia

Starzl TE, Bilheimer DW, Bahnson HT, Shaw BW Jr, Hardesty RL, Griffith BP,
Iwatsuki S, Zitelli BJ, Gartner JC Jr, Malatack JJ, et al

Abstract
A girl aged 6 years 9 months with severe heart disease secondary to homozygous
familial hypercholesterolaemia underwent orthotopic cardiac transplantation and
her liver was replaced with the liver of the same donor. In the first 10 weeks
after transplantation serum cholesterol fell to 270 mg/dl from preoperative
concentrations of more than 1000 mg/dl